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이환규 (공과대학 부학장) 교수 | 죽전

교수소개

Homepage: https://sites.google.com/view/dkubiophysics 분자모델링 (Multiscale molecular dynamics simulation) 기법을 이용하여, 신약개발, 에너지, 나노재료/소재/센서 개발에 관한 연구를 수행. 특히, 나노파티클, 프로틴, 폴리머등 으로 구성된 복합체와 멤브레인과의 상호작용을 이해하고, 그들의 어플리케이션을 위한 최적 상태를 디자인.

교육철학

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강의

년도, 학기, 구분, 교과목명, 학점, 시간표로 구성
년도 학기 구분 교과목명 학점 시간표
2026 1학기 대학 공학멘토링 0 -
2026 1학기 대학 공학수학1 3 월4,5,6/금2,3,4(3공319)
2026 1학기 대학 공학수학1 3 월1,2,3/금5,6,7(3공319)
2026 1학기 대학 일반화학실험1 1 수1,2,3,4(3공320)
2026 1학기 대학 화공시스템실험 2 목11,12,13,14,15,16,17,18(종합실험동202)
2025 2학기 대학 공학멘토링 0 -
2025 2학기 대학 공학수학2 3 월12,13,14/수4,5,6(3공319)
2025 2학기 대학 반응현상실험 2 화15,16,17,18,19,20(종합실험동202202)
2025 2학기 대학 화공분자설계공학 3 금2,3,4,5,6,7(3공520)
2025 2학기 대학 화공분자설계공학 3 월1,2,3,4,5,6(3공520)
2025 2학기 대학 화공종합설계2(졸업논문) 3 수11,12,13,14,15,16(3공519)
2025 1학기 대학 공학멘토링 0 -
2025 1학기 대학 공학수학1 3 수1,2,3/금4,5,6(3공319)
2025 1학기 대학 공학수학1 3 수4,5,6/금1,2,3(3공319)
2025 1학기 대학 이동현상실험 2 화1,2,3,4,5,6,7,8(종합실험동202202)
2025 1학기 대학 일반화학실험1 1 화14,15,16,17(3공204)
2025 1학기 대학 화공시스템실험 2 금13,14,15,16,17,18,19(종합실험동201201)
2025 1학기 대학 화공종합설계1(졸업논문) 3 수11,12,13,14,15,16(3공519)

학력사항

학력사항 목록표 - 학위, 년도, 대학, 학력으로 구성
학위 년도 학력
공학사 2001 중앙대학교 화학공학과
공학석사 2004 Univ. of Michigan Biomedical Engineering (Molecular Modelin
공학박사 2007 Univ. of Michigan Biomedical Engineering (Molecular Modelin

연구분야

고분자 이론 바이오센서 개발 약물전달체 개발 합성생물학

컨설팅 가능분야

분자모델링, 전산화학, 화학정보학 의약화학, 신약 개발, 약물전달체 개발 Polymer 구조 및 물성

연구실적

연구실적
구분 기준일 제목
일반논문 2026-04-17 Effects of Liposome Composition and Size on Protein Corona Formation: Competitive Replacement of Abundant Proteins by High-Affinity Proteins on the Liposome Surface
일반논문 2025-10-22 GENRISE-induced superior extracellular vesicles for scalable therapeutic cargo delivery
일반논문 2025-04-07 Molecular Dynamics Simulations of Protein Corona Formation on Membrane Surfaces: Effects of Lipid Composition and PEGylation on Selective Plasma Protein Adsorption
일반논문 2025-01-06 Effect of PEGylation on the Adsorption and Binding Strength of Plasma Proteins to Nanoparticle Surfaces
일반논문 2024-12-19 Hydrodynamics and Aggregation of Nanoparticles with Protein Corona: Effects of Protein Concentration and Ionic Strength
일반논문 2024-11-15 Crystalline carbon antioxidase mimics enhancing innate anti-inflammatory immunity for the treatment of rheumatoid arthritis
일반논문 2024-11-06 Recent Advances in Simulation Studies on the Protein Corona
일반논문 2024-10-01 Classical and reactive simulations of plastic co-pyrolysis: Effects of polystyrene and its fragments on product yields, aggregation, and reaction mechanisms
일반논문 2024-01-31 Separation of protein corona from nanoparticles under intracellular acidic conditions: effect of protonation on nanoparticle-protein and protein-protein interactions
일반논문 2023-03-08 Differences in protein distribution, conformation, and dynamics in hard and soft coronas: dependence on protein and particle electrostatics
일반논문 2022-07-21 Effects of Lipid Shape and Interactions on the Conformation, Dynamics, and Curvature of Ultrasound-Responsive Liposomes
일반논문 2022-03-24 Mechanistic Pathway of Lipid Phase-Dependent Lipid Corona Formation on Phenylalanine-Functionalized Gold Nanoparticles: A Combined Experimental and Molecular Dynamics Simulation Study
일반논문 2021-11-01 A simple strategy for signal enhancement in lateral flow assays using superabsorbent polymers
일반논문 2021-09-15 Transition-Metal Dichalcogenide Artificial Antibodies with Multivalent Polymeric Recognition Phases for Rapid Detection and Inactivation of Pathogens
일반논문 2021-06-03 Multivalent Nanosheet Antibody Mimics for Selective Microbial Recognition and Inactivation
일반논문 2021-05-01 All-Atom Simulations and Free-Energy Calculations of Antibodies Bound to the Spike Protein of SARS-CoV-2: The Binding Strength and Multivalent Hydrogen-Bond Interactions
일반논문 2021-04-29 Molecular Modeling of Protein Corona Formation and Its Interactions with Nanoparticles and Cell Membranes for Nanomedicine Applications
일반논문 2021-04-27 Reverse Actuation of Polyelectrolyte Effect for In Vivo Antifouling
일반논문 2021-03-30 Effect of Protein Corona on Nanoparticle-Lipid Membrane Binding: The Binding Strength and Dynamics
일반논문 2021-01-01 Topological analysis of single-stranded DNA with an alpha-hederin nanopore
일반논문 2020-11-18 Supramolecular Functionalization for Improving Thermoelectric Properties of Single-Walled Carbon Nanotubes−Small Organic Molecule Hybrids
일반논문 2020-07-01 Heterodimer and pore formation of magainin 2 and PGLa: The anchoring and tilting of peptides in lipid bilayers
일반논문 2020-06-10 Molecular Simulations of PEGylated Biomolecules, Liposomes, and Nanoparticles for Drug Delivery Applications
일반논문 2020-03-12 Effects of Nanoparticle Electrostatics and Protein–Protein Interactions on Corona Formation: Conformation and Hydrodynamics
일반논문 2020-02-21 Supramolecular Protein Assembly Retains Its Structural Integrity at Liquid-Liquid Interface
일반논문 2020-02-19 Quantitative Interpretation of Hydration Dynamics Enabled the Fabrication of a Zwitterionic Antifouling Surface
일반논문 2019-03-28 Self-assembled DNA hollow spheres from microsponges
일반논문 2019-03-01 Effects of hydrophobic and hydrogen-bond interactions on the binding affinity of antifreeze proteins to specific ice planes
일반논문 2019-02-26 Alpha-Hederin Nanopore for Single Nucleotide Discrimination
일반논문 2018-09-12 Disassembly and trimer formation of E2 protein cage: the effects of C-terminus, salt, and protonation state
일반논문 2018-06-07 Structures, dynamics, and hydrogen-bond interactions of antifreeze proteins in TIP4P/Ice water and their dependence on force fields
일반논문 2018-04-25 Effect of low levels of lipid oxidation on the curvature, dynamics, and permeability of lipid bilayers and their interactions with cationic nanoparticles
일반논문 2017-11-01 Modulation of the Vault Protein-Protein Interaction for Tuning of Molecular Release
일반논문 2017-08-28 Effect of lipid shape on toroidal pore formation and peptide orientation in lipid bilayers
일반논문 2017-08-25 In vitro blood cell viability profiling of polymers used in molecular assembly
일반논문 2017-08-01 Adsorption of plasma proteins onto PEGylated single-walled carbon nanotubes: The effects of protein shape, PEG size and grafting density
일반논문 2017-07-19 Multilayer Nanofilms via Inkjet Printing for Stabilizing Growth Factor and Designing Desired Cell Developments
일반논문 2017-06-07 Effects of the asphaltene structure and the tetralin/heptane solvent ratio on the size and shape of asphaltene aggregates
일반논문 2017-04-01 Beneficial roles of H-donors as diluent and H-shuttle for asphaltenes in catalytic upgrading of vacuum residue
일반논문 2017-03-14 Aggregation and insertion of melittin and its analogue MelP5 into lipid bilayers at different concentrations: effects on pore size, bilayer thickness and dynamics
일반논문 2017-03-01 Cytoprotective Self-assembled RGD Peptide Nanofilms for Surface Modification of Viable Mesenchymal Stem Cells
일반논문 2016-11-01 Effect of polyelectrolyte size on multilayer conformation and dynamics at different temperatures and salt concentrations
일반논문 2016-05-09 Adsorption of Plasma Proteins onto PEGylated Lipid Bilayers: The Effect of PEG Size and Grafting Density
일반논문 2016-03-07 Effects of temperature, salt concentration, and the protonation state on the dynamics and hydrogen-bond interactions of polyelectrolyte multilayers on lipid membranes
일반논문 2016-03-01 All-atom simulations and free energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics
일반논문 2015-09-01 Effects of imidazolium-based ionic liquids on the stability and dynamics of gramicidin A and lipid bilayers at different saltconcentrations
일반논문 2015-09-01 Dispersion and bilayer interaction of single-walled carbon nanotubes modulated by covalent and noncovalent PEGylation
일반논문 2015-07-20 Investigation of Ion Channel Activities of Gramicidin A in the Presence of Ionic Liquids Using Model Cell Membranes
일반논문 2015-07-01 Effects of imidazolium-based ionic surfactants on the size and dynamics of phosphatidylcholine bilayers with saturated and unsaturated chains
일반논문 2015-06-01 Structural effects of tachyplesin I and its linear derivative on their aggregation and mobility in lipid bilayers
학술발표 2015-04-09 Simulations of ionic liquids, PEGylated nanotubes and antimicrobial peptides in membranes
일반논문 2015-04-01 Design of a reversible inversed pH-responsive caged protein
일반논문 2015-02-28 The binding and insertion of imidazolium-based ionic surfactants into lipid bilayers: the effects of the surfactant size and salt concentration
학술발표 2015-02-10 Coarse-grained MD simulations of PEGylated coiled coils and their self-assembled micelles
학술발표 2015-01-06 MOLECULAR MODELING OF BIOLOGICAL SYSTEMS FOR NANOMEDICINE APPLICATIONS
일반논문 2015-01-01 Synergistic effects of magainin 2 and PGLa on their heterodimer formation, aggregation, and insertion into the bilayer
학술발표 2014-10-23 분자모델링을 통한 카본나노튜브, 리포솜, 폴리머, 지질막의 상호작용 연구
학술발표 2014-08-12 Molecular modeling of dendrimers and single-walled carbon nanotubes for energy applications
일반논문 2014-07-29 Molecular Dynamics Studies of PEGylated alpha-helical Coiled Coils and Their Self-Assembled Micelles
일반논문 2014-07-28 Formulation Optimization and In Vivo Proof-of-Concept Study of Thermosensitive Liposomes Balanced by Phospholipid, Elastin-Like Polypeptide, and Cholesterol
학술발표 2014-07-01 Molecular modeling of single-walled carbon nanotubes and their interactions with lipids, PEGs, and bilayers
일반논문 2014-03-12 Molecular Modeling of PEGylated Peptides, Dendrimers, and Single-Walled Carbon Nanotubes for Biomedical Applications
일반논문 2014-02-28 Dynamics and stability of lipid bilayers modulated by thermosensitive polypeptides, cholesterols, and PEGylated lipids
학술발표 2014-02-16 MOLECULAR DYNAMICS STUDIES OF PEGYLATED ANTIMICRO BIAL PEPTIDES WITH LIPID BILAYERS.
연구보고서 2014-02-12 열감응성 리포좀 MD simulation
일반논문 2014-01-21 Effect of the structural difference between Bax-a5 and Bcl-xL-a5 on their interactions with lipid bilayers
학술발표 2014-01-15 Modeling of Polypeptide- and Polymer-Conjugated Nanoparticles for Drug Delivery Application
일반논문 2013-12-12 Molecular Dynamics Studies of PEGylated Single-Walled Carbon Nanotubes: The Effect of PEG Size and Grafting Density
일반논문 2013-11-19 The effects of PEGylation on the binding interaction of magainin 2 and tachyplesin I with lipid bilayer surface
학술발표 2013-11-01 Self-assembly of PEGylated lipids and dendrimers
일반논문 2013-10-14 Membrane penetration and curvature induced by single-walled carbon nanotubes: the effect of diameter, length, and concentration
일반논문 2013-10-14 Effect of peptide conformation on TiO2 biomineralization
학술발표 2013-10-10 Molecular simulations of dendrimers, liposomes, and nanotubes grafted with polymers
학술발표 2013-07-22 Molecular modeling of PAMAM dendrimers modified with peptides and polymers
일반논문 2013-06-13 Effect of Arginine Rich Peptide Length on the Structure and Binding Strength of siRNA Peptide Complexes
학술발표 2013-05-03 고분자 결합된 덴드리머, 나노튜브의 모양 및 구조 분석을 위한 분자모델링
학술발표 2013-04-26 Molecular modeling of dendrimers, liposomes, and nanotubes grafted with polymers
학술발표 2013-02-13 Coarse-grained molecular dynamics simulations of PEGylated lipids and dendrimers
일반논문 2013-02-07 Interparticle Dispersion, Membrane Curvature, and Penetration Induced by Single-Walled Carbon Nanotubes Wrapped with Lipids and PEGylated Lipids
일반논문 2012-09-11 Effects of the Size, Shape, and Structural Transition of Thermosensitive Polypeptides on the Stability of Lipid Bilayers and Liposomes
일반논문 2012-06-01 Effects of salt on the size and internal structure of PAMAM dendrimers at different pH
일반논문 2012-06-01 Self-assembly of mixtures of a dendrimer and lipids: effects of hydrophobicity and electrostatics
학술발표 2012-05-10 분자모델링 기법을 통하여, 고분자 결합이 약물전달체의 구조, 물성 및 지질막 상호작용에 미치는 영향 연구
학술발표 2012-04-26 Multiscale simulations of nanoparticles, polymers, and membranes for drug delivery and nanopore applications
일반논문 2012-04-26 Self-Assembly of Lipids and Single-Walled Carbon Nanotubes: Effects of Lipid Structure and PEGylation
일반논문 2012-03-12 Isolating a trimer intermediate in the self-assembly of E2 protein cage
학술발표 2012-02-29 Molecular dynamics studies of the size and internal structure of dendrimers grafted with peptides and PEG
일반논문 2011-11-08 Molecular Dynamics Studies of the Size and Internal Structure of the PAMAM Dendrimer Grafted with Arginine and Histidine
일반논문 2011-06-23 Coarse-Grained Model for PEGylated Lipids: Effect of PEGylation on the Size and Shape of Self-Assembled Structures
학술발표 2011-05-20 Coarse-grained molecular dynamics simulations of PEGylated dendrimers: the size and internal structure of dendrimers, and membrane pore formation
일반논문 2011-04-12 Effects of PEGylation on the Size and Internal Structure of Dendrimers: Self-Penetration of Long PEG Chains into the Dendrimer Core
학술발표 2011-04-07 The effects of PEGylation on the size and internal structure of dendrimers, and membrane pore formation
일반논문 2011-04-07 Membrane Pore Formation Induced by Acetylated and Polyethylene Glycol-Conjugated Polyamidoamine Dendrimers

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