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단국대학교 교원정보

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정선주 (미래융합지식연구소 연구소장) 교수 | 죽전

교수소개

1985년에 서울대학교 자연과학대학 동물학과 (현 생명과학부)에서 이학사를 받은 후 도미하여 1990년에 미국 유타대학교 의과대학에서 생화학 및 분자생물학으로 이학박사를 취득하였다. 1990년도 부터 1993년까지 미국 스탠포드대학교 의과대학 발생생물학과에서 박사후 연구원으로 활동하면서 RNA와 단백질의 상호작용및 세포내 이동에 관한 연구를 수행하였다. 귀국후 서울대학교 유전공학연구소에서 면역세포의 발생과 분화 관련 유전자와 신호전달관련 연구를 수행하였다. 1995년도에 단국대학교 분자생물학과에 부임한 후, 분자생물학과 학과장과 국제교류처 처장 등을 역임하였다. 1997년도 부터 분자세포생물학 실험실을 운영하며 암세포 형성과정에 중요하게 작동하는 RNA 신호전달 방법을 기반으로 한 신개념 항암제를 개발하고 있다. 단국대 부임이후 다수의 국가연구과제를 수행하여, 2007년도에는 과학기술부 국가연구개발 우수성과 100선와 학술진흥재단 우수성과 51선에 선정된 바 있다. 특히 "BK21 RNA 전문인력양성사업팀"의 사업팀장을 맡았고, 교육과학기술부 선정 "국가지정연구실(NRL)"의 책임자로도 활동하였다. 2007년도와 2014년도에 단국대 범은학술상을 수상하였고, 2014년도에는 한국 로레알-UNESCO 여성생명과학상 학술진흥상을 수상한 바 있다. 국제적 우수연구자 집단인 F1000의 chemical biology 의 국내 유일한 faculty member 이기도 하다. 한국 RNA 학회 회장과 한국분자세포생물학회 뉴스지편집위원장 및 출판위원장, 여성생명과학기술포럼 총무위원장, 한국여성과학기술단체 총연합회 총무이사를 역임하였고, 현재는 분자세포생물학회 학술상위원회 위원장, 학회 공식 SCI 학회지 부편집장, 대통령 직속 국가생명윤리심의위원회 위원으로 활동하고 있다.

교육철학

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강의

년도, 학기, 구분, 교과목명, 학점, 시간표로 구성
년도 학기 구분 교과목명 학점 시간표
2026 1학기 대학원 고급핵산공학 3 월19,20,21(소프트102)
2025 2학기 대학원 고급 세포공학 3 월19,20,21(대학원동321)
2025 1학기 대학원 고급핵산공학 3 월19,20,21(미디어101)

학력사항

학력사항 목록표 - 학위, 년도, 대학, 학력으로 구성
학위 년도 학력
이학사 1985 서울대학교 동물생명과학전공
이학박사 1990 University of Utah 생화학과

연구분야

Aptamer sensor 개발 Peptide aptamer 개발 RNA aptamer 개발 면역 조절제 개발 면역세포 신호전달 및 발생과정 심혈관 질환 조절제 개발 암세포 특이적 RNA 발현 기전 유전자 치료 항암제 개발

컨설팅 가능분야

암세포 형성 및 사멸 조절 방안 면역 이상 기능 조절 방안 RNA Aptamer 개발

연구실적

연구실적
구분 기준일 제목
일반논문 2025-12-31 The RNA revolution in medicine: from gene regulation to clinical therapeutics
일반논문 2025-08-01 Dysregulated RNA-binding proteins and alternative splicing: Emerging roles in autism spectrum disorder
일반논문 2023-01-20 ic_linkb 3’UTR Diversity: Expanding Repertoire of RNA Alterations in Human mRNAs
일반논문 2023-01-20 ic_linkb RNA in Biology and Therapeutics
일반논문 2022-11-07 ic_linkb Splicing factor SRSF3 represses translation of p21(cip1/waf1) mRNA
일반논문 2019-12-25 ic_linkb Fabrication of porous scaffold by ternary combination of chitosan, gelatin, and calcium phosphate for tissue engineering
학술발표 2019-10-02 SFSF3 regulates alternative splicing and translation of β-catenin mRNA by 3`UTR dependent manner
학술발표 2019-08-20 p53 pre-mRNA Alternative Splicing is Regulated by SRSF3 and UPF1
학술발표 2019-08-20 Nuclear Localized UPF1 Associates With The Chromatin and Regulates Transcription Elongation Coupled Processes
일반논문 2019-07-01 ic_linkb Nuclear UPF1 Is Associated with Chromatin for Transcription-Coupled RNA Surveillance
일반논문 2019-01-31 Mutation hotspots in the b-catenin gene: lessons from the human cancer genome databases
학술발표 2019-01-18 Role of SRSF3 for RNA decay of p53 alternative spliced mRNA
학술상수상 2018-09-19 KSMCB Excellent Poster Award
학술발표 2018-09-19 Identification of β-catenin mRNA 5’UTR binding proteins
일반논문 2018-06-11 Semivarying coefficient least-squares support vector regression for analyzing high-dimensional gene-environmental data
학술발표 2018-06-01 UPF1 and SRSF3 for RNA decay of p53 alternative spliced mRNA
학술발표 2018-05-31 Role of the p53 alternative spliced isoform in colorectal cancer cells
연구과제 2017-07-01 RNP 기계: β-catenin의 재발견과 새로운 항암 전략
연구과제 2017-06-01 SR 단백질에 의한 mRNA 특이적 translation 조절에 관한 연구(Ez)
일반논문 2017-05-03 WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms
저서/역서 2017-04-28 생물학 명강 라이브 : 어떻게 생명은 작은 변화로 큰 차이를 만드는가. 1
일반논문 2017-01-26 SR Proteins: Binders, Regulators, and Connectors of RNA
일반논문 2016-01-08 SRSF3 represses the expression of PDCD4 protein by coordinated regulation of alternative splicing, export and trans lation
연구과제 2015-12-01 단백질 활성을 조절하는 새로운 non-coding RNA에 의한 Wnt 신호전달계 조절에 관한 연구
연구과제 2015-11-01 암세포에서의 RNA Surveillance 조절에 관한 연구(3/3)
일반논문 2015-09-01 Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells
일반논문 2015-06-11 SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase
지식재산권 2015-04-28 Peptide aptamers against Tenascin-C
일반논문 2015-01-30 HuR represses Wnt/β-catenin-mediated transcriptional activity by promoting cytoplasmic localization of β-catenin
학술상수상 2014-12-24 Wnt/b-catenin signaling regulates the alternative splicing of SRSF3 pre-mRNA
학술발표 2014-12-24 Linking RNA metabolism to Wnt/β-catenin signaling in Cancer
학술발표 2014-12-23 Wnt/β-catenin signaling regulates the alternative splicing of SRSF3 pre-mRNA
학술발표 2014-12-23 Autoregulatory translation of β-catenin mRNA contributes to Wnt-induced β-catenin protein accumulation
학술발표 2014-12-23 Regulation of premature termination codon containing transcripts by Wnt/β-catenin signaling
학술발표 2014-12-23 Functional study on the novel splicing isoform of p53 protein
학술상수상 2014-11-03 2014학년도 범은학술상(특별상)
학술발표 2014-10-23 Alternative Splicing of p53 mRNA and Tumor-Related RNA by β-catenin and SR protein upon Wnt Activation
일반논문 2014-08-01 Correlation of breast cancer subtypes, based on estrogen receptor, progesterone receptor, and HER2, with functional imaging parameters from Ga-68-RGD PET/CT and F-18-FDG PET/CT
학술발표 2014-07-08 Wnt/β-catenin regulates the expression of premature termination codon containing transcripts
학술발표 2014-07-08 Alternative splicing regulation by β-catenin and SR proteins
학술상수상 2014-06-25 2014 L’Oreal-UNESCO 여성생명과학상 학술진흥상
지식재산권 2014-01-14 p53b를 발현하는 세포주 및 이의 생산방법
일반논문 2013-11-29 Splicing factor SRSF3 represses the translation of programmed cell death 4 mRNA by associating with the 5’-UTR region
일반논문 2013-10-31 Multitasking b-catenin: from adhesion and transcription to RNA regulation
학술발표 2013-10-11 Non-coding RNA RMRP in cancer
학술발표 2013-10-10 Translational repression of programmed cell death 4 mRNA by the splicing factor
학술발표 2013-08-30 Cancer-related altered RNA metabolism
연구보고서 2013-07-03 암세포 특이적 RNA 네트워크 발굴 및 제어 기술(5/5)
학술발표 2013-06-21 Translational regulation of β-catenin mRNA upon Wnt signaling
학술발표 2013-06-20 Translational regulation of β-catenin mRNA Wnt signaling
학술발표 2013-06-11 Interplay of oncogenic transcription factor b-catenin with SR protein SRSF3 contributes to the alternative splicing og tumor-related genes.
학술발표 2013-06-11 Splicing factors SRSF3 represses the translations of Programmed Cell Death 4mRNA by associating with the 5’UTR.
지식재산권 2013-04-15 플러렌에 특이적으로 결합하는 RNA 앱타이머 및 이의 용도
일반논문 2012-11-30 β-Catenin and Peroxisome Proliferator-activated Receptor-δ Coordinate Dynamic Chromatin Loops for the Transcription of Vascular Endothelial Growth Factor A Gene in Colon Cancer Cells
학술발표 2012-11-30 Glucose Metabolism Specific Regulation in Cancer
학술발표 2012-11-30 Beta-Catenin is a Cancer-Related RNA Binding Protein
학술발표 2012-11-08 Study on the p53 isoforms in cancer cells
학술발표 2012-10-12 b-CATENIN AS A RNA BINDING PROTEIN : IMPLICATION TO CANCER DEVELOPMENT
학술발표 2012-09-05 Selection and characterization of Tenacin C Binding Peptide for Tumor Targeting
학술발표 2012-08-17 RNA-mediated Mechanism for B-catenin Protein Accumulation by Wnt Signaling
일반논문 2012-08-01 b-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells
학술발표 2012-07-04 Identification of b-catenin specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and its role in cancer cell development
학술발표 2012-06-01 B-catenin recognizes specific RNA motif in cyclooxygenase-2 mRNA 3'UTR and interacts with HuR on colon cancer cells
연구보고서 2012-04-27 바이오마커 특이적 RNA 앱터머 개발(2/2)
학술발표 2012-04-02 Transcriptional and Post-transcriptional Roles of B-catenin by Binding to RNA
학술발표 2012-04-02 Identification of a B-catenin binding RNA motif: Lessons from RNA aptamer and cyclooxygenase-2 mRNA
학술발표 2012-03-06 B-Catenin RNA aptamer: from sequences to Technology
일반논문 2012-01-31 Selection and Characterization of Tenascin C Targeting Peptide
지식재산권 2012-01-18 항-ErbB2 RNA 앱타머 및 이의 용도
학술발표 2011-10-06 Role of B-catenin in RNA Metabolism
일반논문 2011-08-30 Annexin A2 Binds RNA and Reduces the Frameshifting Efficiency of Infectious Brouchitis Virus
지식재산권 2011-08-16 RNA APTAMERS AND THE USES THEREOF
학술발표 2011-07-01 Beta-Catenin binds RNA and regulates RNA metabolism
학술발표 2011-07-01 Post-transcriptional regulation of B-catenin mRNA during Wnt activation
학술발표 2011-06-16 Reduction of Translatability of target mRNA by HuR
학술발표 2011-06-16 B-catenin binds RNA and regulates RNA stability
학술발표 2011-06-16 The Role of B-catenin in cancer-related RNA alternative splicing
학술발표 2011-06-15 Modulation of B-catenin induced transcription and post-transcription by RNA aptamer
학술발표 2011-06-13 Novel functions of B-catenin in RNA metabolism of cancer cells
일반논문 2011-06-01 In Vitro Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells
일반논문 2011-05-01 Persistent anti-tumor effects via recombinant adeno-associated virus encoding herpes thymidine kinase gene monitored by PET-imaging
지식재산권 2011-04-08 p53β를 발현하는 세포주 및 이의 생산 방법
지식재산권 2011-04-08 p53 유사체를 발현하는 세포주 및 이의 생산방법
연구보고서 2011-02-28 나노기반의 압타머 활용기술을 통한 위해성 평가 시스템 개발(3/3)
연구보고서 2011-02-21 암 표적성 AAV 벡터 시스템 개발[2단계(3/3)]
일반논문 2011-02-15 SR Proteins Induce Alternative Exon Skipping through Their Activities on the Flanking Constitutive Exons
일반논문 2010-12-03 NF-κB p65 represses β-catenin-activated transcription of cyclin D1
학술발표 2010-11-30 β-Catenin binds Cyclooxygenase-2 mRNA 3'UTR and recruits HuR to form RNA-protein complex
학술발표 2010-11-30 In vitro selection of RNA aptamer and specific targeting of ErbB2 for breast cancer cell imaging
학술상수상 2010-11-30 β-Catenin binds Cyclooxygenase-2 mRNA 3'UTR and recruits HuR to form RNA-protein complex
지식재산권 2010-11-19 플러렌에 특이적으로 결합하는 RNA 앱타머 및 이의 용도
학술발표 2010-10-07 In vitro selection of RNA aptamers for p53 protein
학술발표 2010-10-07 SF2/ASF mediated alternative splicing of CaMKIIδ in neuronal differentiation of p19 cells
학술발표 2010-09-10 β-Catenin as an RNA Binding Proteins in cancer
지식재산권 2010-09-01 NF-κB의 p50에 결합하는 펩타이드 앱타머
학술발표 2010-08-23 Coordinated Regulation of RNA Metabolism in the Cells
일반논문 2010-07-24 Adiponectin Represses Colon Cancer Cell Proliferation via AdipoR1-and-R2-Mediated AMPK Activation
학술발표 2010-07-12 Role of β-catenin in RNA alternative splicing
연구보고서 2010-05-27 RNA aptamer 발굴 및 대장암 치료제 선도 물질 개발(3/3)
학술발표 2010-05-17 ß-Catenin-mediated Regulation of ER-ß mRNA Transcription and Alternative Splicing
학술발표 2010-05-17 Adiponectin Represses Colon Cancer Cell Proliferation via AdipoR1 and R2-mediated AMPK Activation
지식재산권 2010-05-12 항-테나신 C 펩타이드 및 그의 용도
연구보고서 2010-04-30 NF-kB p50 표적화 펩타이드 앱타머에 의한 염증 유전자 억제 및 심혈관 질환 치료 기반제 제공(2/2)
지식재산권 2010-04-19 PPAR-δ에 결합하는 RNA 앱타머 및 이의 용도
학술발표 2010-03-27 Novel functions of b-catenin in RNA metabolism
학술발표 2010-03-27 RNA Aptamers for the modulation of Wnt/b-catenin Signaling
지식재산권 2010-02-26 Peptide aptamer s Against Tenascin C
지식재산권 2010-01-27 PRC1 유전자 프로모터의 삭제변이 프로모터를 함유하는 암세포 특이적 발현 벡터
일반논문 2009-12-30 A new method for the preparation of bioactive calcium phosphate films hybridized with 1alpha,25-dihydroxyvitamin D3.
학술발표 2009-12-29 Novel Functions of B-catenin in RNA metabolism as revealed by aptamers in colon cancer cells
일반논문 2009-12-13 Bone Nodule Formation of MG63 Cells is Increased by the Interplay of Signaling Pathways Cultured on Vitamin D-3-Entrapped Calcium Phosphate Films
학술발표 2009-11-27 Modulation of Ligand-independent activation pathways by the ErbB2 targeting RNA aptamer
학술발표 2009-11-27 β-Catenin regulates multiple steps of RNA metabolism as revealed by the RNA aptamer in colon cancer cells
학술발표 2009-11-27 Suppression of tumor growth by the tenascin C binding peptide in tumor-specific microenvironment
학술발표 2009-11-27 Anti-cancer effect of the Peroxisome Proliferator-Activated Recepter-δ binding RNA aptamer in colon cancer cells
학술상수상 2009-11-27 KSGT Poster Prize"Suppression of tumor growth by the tenascin C binding peptide in tumor-specific microenvironment"
학술발표 2009-11-27 Development and use of RNA aptamers
학술발표 2009-11-09 Use of RNA aptamers for cancer research
학술발표 2009-11-09 Modulation of oncogenic transcription and alternative splicing by b-catenin and an RNA aptamer in colon cancer cells
학술발표 2009-11-09 Development and utilization of the ErbB2 targeting RNA aptamer for imaging of breast cancer cells
학술발표 2009-11-09 Modulation of target gene expression by the Peroxisome Proliferator -Activated Receptor-δ binding RNA aptamer in colon cancer cells
학술발표 2009-10-16 Biochemical Characterization of RNA Binding Activity of β-catenin
학술발표 2009-10-16 Tenascin C Binding Peptide Targets Tumor Microenvironment and Inhibits Cancer Cell Growth
학술발표 2009-10-16 RNA Cell Biology Coordinated Regulation of Gene Expression
학술발표 2009-10-16 Annexin A2 Binds RNA and Reduces the Frameshifting Efficiency of Infectious Bronchitis Virus
학술발표 2009-10-16 Molecular Characterization of b-catenin Protein Expression in Colon Cancer Cells
학술발표 2009-10-16 Modulation of transcription by the peroxisome proliferator-activated receptor δ-binding RNA aptamer in colon cancer cells
일반논문 2009-09-01 Modulation of transcription by the peroxisome proliferator-activated receptor delta-binding RNA aptamer in colon cancer cells
학술발표 2009-08-25 Development and utilization of the ErbB2 targeting RNA aptamer for imaging of breast cancer cells
학술발표 2009-08-18 Mechanism for SR protein-dependent exon skipping
학술발표 2009-08-18 Transcription and alternative splicing of estrogen receptor-b by b-catenin
학술발표 2009-08-18 Global regulation of RNA alternative slpcing by B-catenin in colon cancer cells
지식재산권 2009-08-07 표적화된 유전자 전달을 위한 아데노-부속 바이러스 혈청형5 벡터
학술발표 2009-07-09 Role of β-catenin in cancer-related RNA alternative splicing
학술발표 2009-06-10 Post-transcriptional regulatory circuit of beta-catenin mRNA by its own 3'-untranslated regios in colon cancer cells
학술발표 2009-06-10 miR-143 in colon cancer cells: possible regulatory mechanism for its expression and function
연구보고서 2009-05-28 암세포 특이적 RNA 네트워크 발굴및 제어 기술(1/5)
일반논문 2009-05-25 Histone H3 N-Terminal Peptide Binds Directly to Its Own mRNA: A Possible Mode of Feedback Inhibition to Control Translation
일반논문 2009-05-06 The RNA aptamer disrupts protein-protein interaciton between b-catenin and nuclear factor-kb p50 and regulates the expression of c-reactive protein
지식재산권 2009-05-01 항-ErbB2 RNA 앱타머 및 이의 용도
연구보고서 2009-04-29 세포암화 및 밤낮주기조절에서의 RNA decay 조절 기전 연구(3/3)
일반논문 2009-04-01 Use of RNA aptamers for the modulation of cancer cell signaling
학술발표 2009-03-27 Development of Targeting RNA Aptamers for ErbB2 Protein
일반논문 2009-03-01 Emerging roles of RNA and RNA-binding protein network in cancer cells
연구보고서 2009-02-25 RNA전문인력양성사업 (2단계 BK21 3차년도)
연구보고서 2009-02-23 NF-kB p50 표적화 펩타이드 앱타머에 의한 염증 유전자 억제 및 심혈관 질환 치료 기반제 제공(1/2)
연구보고서 2009-02-23 암 표적성 AAV 벡터 시스템 개발 [2단계(1/3)]
일반논문 2008-11-01 Effects of Asymmetric Arginine Dimethylation on RNA-Binding Peptides
학술발표 2008-10-10 β-Catenin and NF-kB p50 Control the Expression of Atherogenesis-related Genes
학술발표 2008-10-10 Generation and Function of an Alternatively Spliced P53 mRNA in Cancer Cells
학술발표 2008-10-10 Expanding the Role of β-catenin in Multiple Steps of RNA Metabolism
학술발표 2008-10-10 Emerging Roles of RNA Metabolism Network in Cancer Cells
학술발표 2008-10-10 Development of Peroxisome-proliferator-activated Receptor-δ Target-ing RNA Intramers in Colon Cell Lines
학술발표 2008-10-10 Annexin A2 Binds RNA Pseudoknot and Modulates the Frameshifting and Translation of RNA
학술발표 2008-10-10 Adiponectin Suppresses Proliferation of Colon Cancer Cells through AMPK Activation
학술발표 2008-10-10 Specific Protein-Protein Interaction between Bcl-3 and p50 Submit of NF-kB
학술발표 2008-10-10 Signal Induced Alternative Splicing of Estrogen Receptor-βmRNA
학술발표 2008-10-10 Regulation of β-catenin Gene Expression by the Alternative 3'-untranslated Regions
학술발표 2008-09-29 Multiple function of b-catenin for the significantly altered gene expression in cancer cells
지식재산권 2008-08-22 Peptide Aptamers against Tenascin C
저서/역서 2008-08-06 2008-1학기 사이버강의(세포생물학)
지식재산권 2008-08-01 Adeno-Associated Virus Serotype 5 Vector for Targeted Gene Delivery
학술발표 2008-07-28 Altered mRNA splicing and stability by b-catenin in colon cancer cells
지식재산권 2008-07-25 NF-kB의 p50에 결합하는 펩타이드 앱타머
학술발표 2008-06-12 Altered RNA Metabolism in Cancer Cells
연구보고서 2008-05-25 Beta-catenin에 의한 RNA alternative Splicing에 대한 연구(2/2)
연구보고서 2008-05-13 RNA전문인력양성사업 (2단계 BK21 2차년도)
학술발표 2008-05-07 β- Catenin-induced aberrant RNA metabolism in colon cancer Cells
학술발표 2008-05-07 In Vistro selection and intracellular espression of PPARδ targeting RNA aptamers in colon cancer cell lines
연구보고서 2008-04-28 심혈관질환 진단 및 치료를 위한 펩타이드 앱타머 개발(2/2)
지식재산권 2008-04-07 표적화된 유전자 전달을 위한 아데노-부속 바이러스 혈청형 5백터
지식재산권 2008-03-20 PPAR-δ에 결합하는 RNA 앱타머 및 이의 용도
지식재산권 2008-02-21 RNA APTAMERS AND THE USES THEREOF
연구보고서 2008-02-19 암 표적화 기술소재 개발 및 검증(3/3)
연구보고서 2008-01-15 세포암화 및 밤낮주기조절에서의 RNA decay 조절 기전 연구(2/3)
일반논문 2008-01-01 Cancer gene therapy using adeno-associated virus vectors
지식재산권 2007-12-21 FLASH의 활성을 억제하여 세포의 아폽토시스를 조절하는 방법
일반논문 2007-12-15 An RNA aptamer that recognizes a specific conformation of the protein calsenilin
학술상수상 2007-12-13 2007년 한국학술진흥재단 우수성과
학술상수상 2007-11-02 2007학년도 범은학술상(산학협력부문)
학술상수상 2007-10-29 과학기술부 국가연구개발 우수성과
학술상수상 2007-10-19 2007년도 한국분자세포생물학회 추계학술대회 우수포스터상
학술발표 2007-10-18 Annexin A2 Binds Pseudoknot RNA and Modulates the Frameshifting of Viral RNA
학술발표 2007-10-18 β-Catenin regulates multiple steps of RNA metabolism as revealed by the RNA aptamer in colon cancer cells
학술발표 2007-10-18 β-Catenin binds to the downstream region and regulates the expression C-reactive protein gene
학술발표 2007-10-18 Expression of colony-stimulating factor (CSF)-1 protein by TNF-a induced protein-protein interaction
학술발표 2007-10-18 In vitro selection and characterization of ErbB2 binding RNA aptamers
학술발표 2007-10-18 Identification of Novel Tumor targeting peptide aptamer for human tenascin C protein
학술발표 2007-10-18 In vitro selection and intracellular expression of PPARδ targeting RNA Intramers in colon cancer cell lines
일반논문 2007-10-02 β-Catenin regulates multiple steps of RNA metabolism as revealed by the RNA aptamer in colon cancer cells
일반논문 2007-09-30 Efficient gene expression by self-complementary adeno-associated virus serotype 2 and 5 in various human cancer cells
지식재산권 2007-08-28 항-테나신 c 펩타이드 앱타머
저서/역서 2007-08-24 2007-1학기 사이버강의(세포생물학)
학술발표 2007-08-22 Alternative splicing of Estrogen Receptor-β mRNA in colon cancer cells
일반논문 2007-08-17 β-Catenin binds to the downstream region and regulates the expression C-reactive protein gene
지식재산권 2007-07-12 RNA 앱타머 및 그의 용도
저서/역서 2007-07-10 당신의 유전자는 안녕하십니까?(한국유전학회 총서 제11권)
학술발표 2007-06-21 Role of β-catenin in RNA alternative splicing and stability
학술발표 2007-06-08 b-catenin binding RNA aptamer reveals novel RNA-protein interactions in colon cancer cells
학술발표 2007-05-30 Self-Complementary Adeno-Associated Virus Serotypes Can Induce Efficient Long-Term Therapeutic Effects in Human Cancer Cells
학술발표 2007-05-30 Development of Tenascin-C Binding Peptide Aptamers as the Tumor Targeting Tools
학술발표 2007-05-29 β-Catenin bind to RNA and regulares the stability of COX-2 mRNA
학술발표 2007-04-27 RNA Aptamers Regulate the RNA Metabolism in Colon Cancer Cells
일반논문 2007-04-18 a-Helical peptide containing N, N-dimethyl lysine residues displays low-nanomolar and highly specific binding to RRE RNA
연구보고서 2007-03-12 Beta-catenin에 의한 RNA alternative Splicing에 대한 연구(1/2)
일반논문 2007-03-01 RNA 앱타머(Aptamer): 간단한 원리부터 복잡한 응용까지
연구보고서 2007-02-28 세포암화 및 밤낮주기조절에서의 RNA decay 조절 기전 연구(1/3)
학술발표 2007-02-27 β-Catenin regulares the expression of C-Reactive Protein mRNA by long-range interaction with the NF-κB p50 subunit
연구보고서 2007-02-27 암 표적화 기술소재 개발 및 검증(2/3)
학술발표 2007-02-27 β-Catenin stabilizes Cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3’UTR
연구보고서 2007-02-24 심혈관질환 진단 및 치료를 위한 펩타이드 앱타머 개발
학술발표 2007-01-21 Therapeutic RNA aptamer regulates b-catenin-mediated RNA metabolism in colon cancer cells
지식재산권 2006-12-05 TCF-1의 베타 카테닌과 상호작용하는 부위에 대한 RNA 앱타머와 그 용도
학술발표 2006-12-01 b-Catenin specific RNA aptamer as a novel tool for the cancer gene therapeutics
학술발표 2006-11-18 Regulation of RNA expression and development of RNA aptamer for molecular imaging
일반논문 2006-11-01 Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells.
일반논문 2006-11-01 Modulation of oncogenic transcription and alternative splicing by b-catenin and the RNA aptamer in colon cancer cells
일반논문 2006-11-01 β-Catenin stabilizes Cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3’UTR
학술발표 2006-10-12 In vitro selection of RNA aptamer to phosphrylated Ca2+/Camodulin-dependent protein kinase Ⅱ
학술발표 2006-10-12 Protein-protein interaction between NF-kB p50 subunit and B-catenin
학술발표 2006-10-12 Regulation of gene expression by alternative untranslated regions of B-catenin
학술발표 2006-10-12 Alternative Splicing of Ca2+/Camodulin-dependent protein kinase Ⅱ-δ mRNA
학술발표 2006-10-12 B-Catenin stabilizes Cyclooxygenase-2 mRNA via its 3'UTR
학술발표 2006-10-12 Cancer gene therapy using adeno-associated virus serotype 2(AAV2)-mediated anti-angiogenesis approaches
학술발표 2006-10-12 Development of Tenascin-C binding peptide aptamers for the tumor targeting tools
학술발표 2006-10-12 Emerging roles of B-catenin and RNA aptamers in RNA metabolism
학술발표 2006-10-12 Etoposide induced PI-3kinase/Akt activation mediates the nuclear translocation of NF-kB p50 subunit
학술발표 2006-10-12 Exprission of C-Reactive Protein by TNF-a induced chromatin looping
학술발표 2006-10-12 Identification of IBV pseudoknot RNA binding proteins and characterization of its role in ribosomal frameshifting
학술발표 2006-10-12 In vitro selection and intracellular expression of PPAR δ targeting RNA aptamers in colon cancer cell lines
학술발표 2006-09-30 Modulation of oncogenic transcription and alternative splicing by B-catenin and the RNA aptamer in colon cancer cells
학술발표 2006-09-30 Novel Role of B-Catenin in mRNA Stabilization:Direct binding to Cyclooxygenase-2 mRNA
학술상수상 2006-09-30 RNA Chemistry meets Biology POSTER PRIZE
지식재산권 2006-09-05 carbohydrate-specific peptides which have a strong affinity and preparations method thereof
일반논문 2006-09-01 Intracellular expression of the T-cell factor-1 RNA aptamer as an intramer
연구보고서 2006-06-30 Beta-catenin에 의한 세포암화 조절 및 신개념 RNA 조절 네트워크 탐색(2차년도)
학술발표 2006-06-20 Regulation of mRNA alternative splicing by b-catenin and RNA aptamers
학술발표 2006-05-26 Modulation of b-catenin by XIAP (X-linked inhibitor of apoptosis protein) induced NF-kB activation
학술발표 2006-05-25 Transcription of CRP gene by specific looing of enhancers and protein-protein intractions
일반논문 2006-05-19 Suppression of Receptor-mediated Apoptosis by Death effecter domain Recruiting Domain Binding Peptide Aptamer,
일반논문 2006-03-28 Role of PI3-kinase/Akt pathway on the activation of etoposide-induced NF-kB transcription factor
연구보고서 2006-02-20 암 표적화 기술소재 개발 및 검증(세부)
학술발표 2006-02-17 RNA aptamers, novel RNA-protein interactions and emerging roles of RNA metabolism
연구보고서 2005-11-21 바이오 분석칩을 위한 aptamer 개발
일반논문 2005-10-31 PI3-kinase and PDK-1 regulate HDAC1-mediated transcriptional repression of transcription factor NF-kB
학술발표 2005-10-19 Specific modulation of Wnt signaling by the b-catenin binding RNA intramer in colon cancer cell lines
학술발표 2005-10-17 In vitro selection of RNA aptamer to the phosphorylated Ca2+/Camodulin-dependent protein kinase ll
학술발표 2005-10-17 In vitro selection of RNA aptamer for peroxisome-proliferator-activated receptor delta
학술발표 2005-10-17 Identification and characterization of IBV pseudoknot RNA binding proteins and its role in ribosomal frame shifting
학술발표 2005-10-17 Effects of the Beta-3 Adrenergic Receptor / Beta-2 Adrenergic Receptor and PPAR on Obesity in Korean Women
학술발표 2005-10-17 Study on potential roles of the micro RNA in colon cancer cell lines
학술발표 2005-10-17 Specific transcriptional activation of NF-κB p50 subunit-dependent target genes
학술발표 2005-10-17 Specific regulation of β-catenin-mediated transcription by XIAP
학술발표 2005-10-17 Selection and Characterization of the Peroxiredoxin 1 Binding Peptide Aptamers
학술발표 2005-10-17 Production and Characterization of Monoclonal Antibodies against Human N-terminal pro B-type natriuretic peptide
학술발표 2005-10-17 Post-transcriptional regulation of cyclooxygenase-2 mRNA by β-catenin
지식재산권 2005-10-04 베타아밀로이드 특이 단일 클론 항체 및 그의 제조방법
일반논문 2005-08-31 Identification of the +1 ribosomal frameshifting site of LRV1-4 by mutational analysis
학술발표 2005-06-11 Development of the phage display peptide as a cancer targeting tool
일반논문 2005-06-01 Etoposide-induced apoptosis resistance by the PI3-kinase/Akt activated NF-kB p50 subunit
저서/역서 2005-05-15 옥수수밭의 처녀 맥크린토크
학술발표 2005-05-13 Development of the phage displayed peptide as an inhibitor of MCP-1 (Monocyte Chemoattractant Protein-1) mediated angiogenesis
일반논문 2005-04-29 Inhibition of the DNA binding by the TCF-1 binding RNA aptamer
학술발표 2005-04-19 Modulation of Wnt signaling by the RNA aptamers
일반논문 2005-03-14 Inhibition of the angiogenesis by the MCP-1 (Monocyte Chemoattractant Protein-1) binding peptidebinding peptide
일반논문 2005-03-01 b-catenin as a valid molecular target for the development of therapeutic inhibitors
일반논문 2005-02-04 An RNA aptamer that binds to the b-catenin interaction domain of TCF-1 protein
연구보고서 2005-01-02 나노바이오칩에 응용을 위한 Aptamer 기술개발(2/2)
학술발표 2004-11-26 Modulation of TCF/β-catenin signaling by the RNA aptamers
학술발표 2004-10-15 Specific modulation of the FLASH-mediated apoptosis and signaling by the intracellular expressed peptide aptamer
학술발표 2004-10-15 Specific Inhibition of Monocyte Chemoattractant Protein-1 Mediated Angiogenesis by the Peptide Aptamer
학술발표 2004-10-15 Characterization of plant proteins binding to TMV pseudoknot RNA
학술발표 2004-10-15 In vitro selection of RNA aptamer to Ca2+/Camodulin-dependent protein kinase Ⅱ
학술발표 2004-10-15 PI3 kinase/Akt mediates NF-kB activation through serine phosphorylation on p50 subunit
학술발표 2004-10-15 In vitro selection of RNA and peptide aptamers for Peroxiredoxin 1
학술발표 2004-10-15 In vitro charaterization of TCF-1 and β-catenin binding RNA aptamers
학술발표 2004-10-15 RNA-protein interaction assays for the identification of pseudoknot RNA binding proteins
학술발표 2004-10-15 Inhibition of tumorigenesis by the Armadillo Domain Binding RNA Aptamer in colon cancer cells
학술발표 2004-10-15 Interrelation of β-catenin and XIAP in colon cancer cells
일반논문 2004-09-15 Predicting genes expressed via -1 and +1 frameshifts
일반논문 2004-08-01 Inhibition of the functions of the nucleocapsid protein of human immunodeficiency virus-1 by an RNA aptamer
학술발표 2004-07-09 Development of Nucleocapsid protein binding RNA aptamers
지식재산권 2004-06-02 제1형 인간면역결핍 바이러스의 뉴클레오캡시드 단백질에 결합하는 RNA
학술발표 2004-06-01 βcatenin binding RNA aptamer as a tool for modulating of tumorigenesis
학술발표 2004-05-27 RNA aptamers for modulation of cell signaling
연구보고서 2004-05-26 MCP-1에 결합하여 기능을 저해하는 펩타이드의 개발(2/2)
일반논문 2004-02-29 In vitro selection and characterization of TCF-1 binding RNA aptamer
일반논문 2004-02-25 An approach to enhance specificity against RNA targets using heteroconjugates of aminoglycosides and chloramphenicol (or linezoloid)
연구보고서 2004-02-24 나노바이오칩에 응용을 위한 Aptamer 기술개발(1/2)
일반논문 2004-02-01 NF- κB전사 조절의 새로운 패러다임
학술발표 2003-12-17 RNA intramer specifically modulates the b-catenin-mediated transcription and the protein-protein interaction in the colon cancer cells
일반논문 2003-12-01 RNA aptamers that bind the nucleocapsid protein contain pseudoknots
일반논문 2003-11-21 DNA-specific autoantibody cleaves DNA by hydrolysis of phosphodiester and glycosidic bond
학술발표 2003-11-14 RNA aptamer as atool for modulating cellular signaling in the colon cancer cells
학술발표 2003-10-10 RNA intramer specifically modulates the β-catenin-mediated transcription and the protein-protein interaction in the colon cancer cells
학술발표 2003-10-10 Activation of Akt pathway in Response to Etoposide leads to Phosphorylation of p50 Subunit of NF-kB
학술발표 2003-10-10 Reciprocal Repression of NF-κB and β-catenin/TCF Transcription Factors
학술발표 2003-10-10 DNA-specific auto-antibody cleaves DNA by hydrolysis of phosphodiester bond or glycosidic bond
학술발표 2003-10-10 Selective RNA Aptamer Binds to the HMG Domain and Specifically Modulates the Transcriptional Function of TCF-1 Protein
학술발표 2003-10-10 In Vitro Selection of RNA Aptamers for β-catenin /TCFProtein Interaction as a Specific Targeting Molecule
학술상수상 2003-10-10 2003 한국분자세포생물학회 우수포스터상
학술발표 2003-10-10 In vitro Characterization and Intracellular Expression of the Nucleocapsid Protein Binding RNA Aptame
학술발표 2003-10-10 Specific Regulation of MCP-1 Functions by the Peptide Aptamer against the Monocyte Chemoattractant Protein (MCP-1)
학술발표 2003-07-10 Specific modulation of Wnt signaling by the b-catenin binding RNA intramer
학술발표 2003-05-14 Cross-talk between transcription factors for the regulation of signaling network
학술발표 2003-05-14 In vitro selection of the RNA aptamer to the b-catenin binding domain of Tcf protein
학술발표 2003-05-14 Searching for high affinity ligands employing mix-and-match library: NC-binding RNA aptamer as a model system
학술발표 2003-04-30 RNA aptamer as a specific modulator of Wnt signaling mediated carcinogenesis
연구보고서 2003-04-13 HIV의 Nucleocapsid 단백질에 결합하는 Aptamer RNA 개발(Selex 기법을 이용한 HIV Packaging을 저해하는 Aptamer RNA개발)
연구보고서 2003-03-15 MCP-1에 결합하여 기능을 저해하는 펩타이드의 개발(1/2)
저서/역서 2003-03-15 생물정보학 -유전자와 단백질 분석에 관한 실용지침서-
일반논문 2003-01-10 Specific modulation of the anti-DNA autoantibody-nucleic acids interaction by the high affinity RNA aptamer
일반논문 2002-12-01 RACK-1, a receptor for activated C kinase, interacts with the transcription factor NFAT and represses its transactivation
일반논문 2002-11-27 Mimicry of tanden repeat peptides against cell surface carbohydrates
학술발표 2002-11-07 Modulation of Wnt/β-catenin signaling by the armadillo domain binding RNA aptamer
일반논문 2002-10-31 Ribozyme-mediated replacement of p53 RNA by targeted trans-splicing
학술발표 2002-10-17 Specific modulation of the receptor-mediated apoptosis by the intracellular expressed peptide aptamer to the FLASH protein
학술발표 2002-10-17 Specific peptide aptamer for the MCP-1 as a regulator for the atherosclerosis
학술발표 2002-10-17 Stabilization of the HIV-1 nucleocapsid binding RNA aptamer by circularization and by intramer expression
학술발표 2002-10-17 Etoposide-induced activation of the NFkB transcription factor via the PI3K/Akt pathway
학술발표 2002-10-17 Specific regulation of the TCF-1 (T-cell factor-1) transcription factor by the HMG domain binding RNA aptamer
학술발표 2002-10-17 Modulation of the anti-DNA autoantibody by the in vitro selected RNA aptamer
지식재산권 2002-07-22 카나마이신 A 에 특이적으로 결합하는 RNA 서열
지식재산권 2002-07-22 시알린 루이스X(sLeX)에 특이적으로 접합하는 RNA 서열
지식재산권 2002-07-12 Cholesterol 또는 이의 그 유도체에 특이하게 결합하는 RNA 서열 및 이를 이용한 친지성물질의 탐지방법
연구보고서 2002-06-30 대학.학부 및 전공별 특성화 위원회 연구
지식재산권 2002-05-01 N-acetylneuramin-Lactose에 접합하는 RNA 분자
지식재산권 2002-05-01 안티-DNA 자가항체에 특이적으로 결합하는 RNA 분자
학술발표 2002-03-14 Specific detection of the cancer cell surface sugar antigen with the peptide and RNA aptamers
일반논문 2002-03-08 Selection and Stabilization of the RNA aptamers agaginst the Human Immunodeficiency Virus Type-1 Nucleocapsid protein
학술발표 2001-10-11 Mimicry of Tandem Repeat Peptides against Sialy1 Lewis X
학술발표 2001-10-11 Inhibition of Wnt Signaling by the RNA Aptamers against the β-catenin and TCF Proteins
학술발표 2001-10-11 Development of Apoptosis Modulating RNA and Peptide Aptamers
학술발표 2001-10-11 Development of the Packaging Inhibitor by RNA Aptamers against the Nucleocapsid Protein of HIV-1
학술발표 2001-10-11 Suppression of the Etoposide-Induced Apoptosis by the Activation of the Tcf Transcription Factor
일반논문 2001-07-01 미토콘드리아의 새로운 작용을 이용한 신약개발 전략
일반논문 2001-06-30 In vitro selection of RNA against Kanamycin B
학술발표 2001-06-03 A prototype retargeted adenoviral vector interacting with a tumor antigen Sialyl Lewis X
일반논문 2001-04-30 b-catenin에 의한 신호전달과 그 역할
저서/역서 2001-02-25 생명과학
일반논문 2001-02-01 In Vitro Selection of the RNA Aptamer against the Sialyl Lewis X and Its Inhibition of the Cell Adhesion
일반논문 2000-12-01 Transcriptional regulation and apoptosis induction by Tcf/beta-catenin complex in various T-cells.
학술발표 2000-10-18 Development of TCF-1 binding RNA as a tool for the regulation of transcription activity of TCF-1/beta-catenin complex in the cells
학술발표 2000-10-13 RNA aptamer for HIV-1 nucleocapsid as a specific and high affinity inhibitor of nucleocapsid protein/psi RNA binding in vivo
학술발표 2000-10-13 Development of sialyl Lewis X binding RNA and peptides as specific inhibitors of cell adhesion
학술발표 2000-09-24 Development of RNA aptamers which bind to the pathogenic molecules of immune cells
저서/역서 2000-02-21 분자생물학
일반논문 1999-11-24 Cholesterol esterase acitvity by in vitro selection of RNA against a phsphate transition-state analogue.
학술발표 1999-10-25 Development of the immunoregulratory therapy utilizing the RNA combinatorial library
학술발표 1999-10-25 In vitro selected RNA aptamer specifically binds to sialyl Lewis X sugar moiety and inhibits selectin/ligand adsorption of HL60 cells
학술발표 1999-10-25 In vitro selection of RNA aptamer which has nanomolar binding affinity to anti-DNA autoantibody from MRL/lpr autoimmune mouse model for SLE
학술발표 1999-10-25 Development of Trans-splicing ribozyme targeted to the tumor suppressor gene
일반논문 1999-04-30 Isolation of Developmentally Regulated Novel Genes Based on Sequence Identity and Gene Expression Pattern
학술발표 1999-04-30 Protein-RNA interaction analysis using Biosensor
연구보고서 1999-04-20 핵산라이브러리를 이용한 세포접합 차단제의 개발
일반논문 1999-02-28 In vitro selection of RNA against the glycosidase antibody
학술발표 1999-02-21 Glycosidase Antibodies Using in Vivo and In Vitro Immunization
학술발표 1999-02-08 In Vitro Selection of RNA for Biologically Interesting Small Molecules and Evaluation of Binding via Surface Plasmon Resonance
일반논문 1999-01-31 Picomolar Scale Determination of Carbohydrates Covalently Immobilized on Activated Beads Using Hydoxyl Functionality
저서/역서 1999-01-10 필수 세포생물학
연구보고서 1998-11-30 T세포의 apoptosis 유도에 따른 TCF-1 유전자 발현의 조절에 관한 연구-2
학술발표 1998-10-24 Selection of High Affinity RNA Binder to the Carbohydrate Molecule from the Combinatorial RNA Library
학술발표 1998-10-24 Reduction of Tcf-1 Expression is Responsible for the Down-Modulation of TCR/CD3 Complex during T-cell Apoptosis
일반논문 1998-10-01 Expression of Tcf-1 mRNA and surface TCR-CD3 complexes are reduced during apoptosis of T cells
일반논문 1998-09-01 Whole-mount in situ Hybridization of Mitochondrial rRNA and RNase MRP RNA in Xenopus Laevis Oocytes
일반논문 1998-09-01 Down-regulation of Tcf-1 Expression by Activation-induced Apoptosis of T cell Hybridoma
학술발표 1998-04-25 In Vitro Selection of Sialyl-Lewis X Specific RNA Molecules
학술발표 1998-04-18 Down-regulation of Tcf-1 and surface TCR/CD3 Complex during Apoptosis of T-cell
일반논문 1998-03-01 A glycosidase antibody elicited against a chair-like transition state analog by in vitro Immunization
저서/역서 1998-02-25 분자세포생물학
학술발표 1997-12-15 Expression of murine Tcf-1 gene is specifically reduced during calcium-ionophore induced apotosis of
연구보고서 1997-11-25 T세포의 apoptosis 유도에 따른 TCF-1 유전자 발현의 조절에 관한 연구-1
학술발표 1997-10-18 Expression of murine Tcf-1 gene is Specifically reduced during apoptosis of T-cell hybridoma
일반논문 1997-09-01 Antibody-catalysed glycosyl transfer reactions from in vitro immunization
일반논문 1997-06-30 Transcription and Export of RNase MRP RNA in Xenopus laevis Oocyte
연구보고서 1996-12-20 T세포 분화과정에 있어서의 TCF-1유전자 발현조절에 의한 세포의 죽음에 관한 연구
저서/역서 1996-12-15 유전자:생명의 원천(한국유전학회총서 4)
학술발표 1996-10-26 Down Regulation of TCF-1 & CD3-e Expression durings apoptosis in T-cell Hybridoma
일반논문 1996-08-28 Preparation of Antibodies with Glycosidase Activity Using in Vitro and in Vivo Immunizations
일반논문 1996-07-30 Regulation and function of the mitochondrial genome
학술발표 1996-05-09 Preparation of antibodies with glycosidase activity using in vitro and in vivo immunizations
일반논문 1996-04-01 Subtle determinants of the nucleocytoplasmic partitioning of in vitro transcribed RNase MRP in Xenop
학술발표 1995-10-20 Expression of CD3 and TCF-1 during apoptosis induced in T-cell hybridoma.
일반논문 1995-07-01 촉매항체와 라이보자임
일반논문 1995-07-01 Distribution of RNase MRP RNA during Xenopus laevis oogenesis
일반논문 1995-05-01 분자조합을 이용한 신약개발
일반논문 1994-10-02 Repair of heteroduplex DNA in Xenopus laevis oocytes.
일반논문 1994-10-01 Distribution of exchanges upon homologous recombination of exogenous DNA in Xenopus laevis oocytes.
일반논문 1992-12-01 Effect of terminal nonhomologies on homologous recombination in Xenopus laevis oocytes.
일반논문 1992-10-25 Characterization of a Xenopus laevis ribonucleoprotein endoribonuclease.
학술발표 1992-06-04 Expression of RNAse MRP RNA during Xenopus development.
학술발표 1992-05-27 Identification of the RNase MRP activity: Isolation of the RNA component and its abundance during de
일반논문 1992-01-01 Tests of the double-strand-break repair model of recombination in Xenopus laevis oocytes.
학술발표 1989-07-07 Tests of the Double-strand-break repair recombination and other models of homologous recombination i
학술발표 1989-03-20 The effect of terminal nonhomology on homologous recombination in Xenopus laevis oocytes.

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