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단국대학교 교원정보

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교수소개

대학원 박사과정중 세포내 에너지와 활성산소를 생산하는 미토콘드리아의 전자전달계 효소인 시토크롬 씨 옥시다제의 활성을 조절하는 기작을 연구하였습니다. 그후 연구원과정동안 암과 뇌질환등 인간의 여러질병들과 미토콘드리아 기능이상의 상관관계에 대해서 연구했습니다. 또한 시토크롬 씨 옥시다제의 폐조직특이적 동위효소의 기능을 유전자형질변형 생쥐연구를 통해서 밝혀내었습니다. 그리고 뇌졸증과 심장마비후 야기되는 세포파괴를 막을수 있는 원적외선 치료를 연구하여 미국 특허를 출원했습니다. 현재 여러 질병에서 보여지는 미토콘드리아의 기능장애 기작을, 특히 세포신호체계의 역할에 대해서 연구하고 있습니다.

교육철학

고등교육의 목표는 생명의 존엄성을 인지하고, 사명감과 책임감을 가지며, 전문적인 지식과 기술을 습득하고, 논리적 분석과 객관성을 바탕으로 창의적으로 문제를 해결하수 있는 능력을 갖춘 인재를 양성하는 것이라고 생각합니다. 단국 대학교의 ‘세계로 도약하는 민족사학’이라는 교육비전 하에 학생들이 현대사회의 치열한 경쟁 속에서도 더불어 협동하며, 지역사회 그리고 더 나아가 세계, 인류사회의 발전에 공헌할 수 있는 인재로 커 나가도록 교육자로서 돕는 것이 교육 철학이자 목표입니다.

강의

년도, 학기, 구분, 교과목명, 학점, 시간표로 구성
년도 학기 구분 교과목명 학점 시간표
2025 2학기 대학 감염과면역2 5 목1,2,3,5,6,7(의334)
2025 2학기 대학 의학사속의대발견 3 목19,20,21
2025 1학기 대학 DK로드맵 1 월15,16,17,18(의332)
2025 1학기 대학 기초의학입문 1 월1(의110)
2025 1학기 대학 의학사속의대발견 3 목19,20,21(자연1관215)
2025 1학기 대학 인간역사속의의학이야기 2 화19,20
2025 1학기 대학 인간예술의과학적접근 3 수19,20,21(사범205)
2024 2학기 대학 인간역사속의의학이야기 2 화19,20
2024 2학기 대학 인간예술의과학적접근 3 수19,20,21(사범206)
2024 1학기 대학 의학사속의대발견 3 목19,20,21(자연1관215)
2024 1학기 대학 의학사속의대발견 3 목7,8,9,10,11,12(국제102)
2024 1학기 대학 인간역사속의의학이야기 2 화19,20

학력사항

학력사항 목록표 - 학위, 년도, 대학, 학력으로 구성
학위 년도 학력
이학사 1996 숙명여자대학교 물리·화학·생물학과군
이학석사 1998 숙명여자대학교 물리·화학·생물학과군
이학박사 2001 Philipps - Univ. Marburg 화학과 생화학전공

연구분야

Cell signaling pathways targeting mitochondria Cellular respiration in cancers & neurodegenerative diseases Signal transduction targeting mitochondria in human diseases Tissue specific isozymes

컨설팅 가능분야

Enzyme biochemistry Mitochondrial bioenergetiecs Signal transduction

연구실적

연구실적
구분 기준일 제목
일반논문 2025-02-04 Cardiac Tyrosine 97 Phosphorylation of Cytochrome c Regulates Respiration and Apoptosis
일반논문 2024-12-01 Regulation of mitochondrial oxidative phosphorylation through tight control of cytochrome c oxidase in health and disease - Implications for ischemia/reperfusion injury, inflammatory diseases, diabetes, and cancer
일반논문 2024-07-14 Prostate Cancer-Specific Lysine 53 Acetylation of Cytochrome c Drives Metabolic Reprogramming and Protects from Apoptosis in Intact Cells
일반논문 2023-12-14 Modulation of mitochondrial function with near-infrared light reduces brain injury in a translational model of cardiac arrest
일반논문 2023-07-13 Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle
일반논문 2023-05-01 Non-invasive treatment of ischemia/reperfusion injury: Effective transmission of therapeutic near-infrared light into the human brain through soft skin-conforming silicone waveguides
일반논문 2022-10-01 Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury
일반논문 2021-08-01 Mitochondrial respiration is controlled by Allostery, Subunit Composition and Phosphorylation Sites of Cytochrome c Oxidase: A trailblazer's tale - Bernhard Kadenbach
일반논문 2021-06-01 Regulation of Cytochrome c Oxidase by Natural Compounds Resveratrol, (-)-Epicatechin, and Betaine
일반논문 2021-04-01 Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis
일반논문 2021-01-01 Rutin inhibits DRP1-mediated mitochondrial fission and prevents ethanol-induced hepatotoxicity in HepG2 cells and zebrafish
일반논문 2020-11-01 Cytochrome c oxidase-modulatory near-infrared light penetration into the human brain: Implications for the noninvasive treatment of ischemia/reperfusion injury
일반논문 2020-08-01 Brain-Specific Serine-47 Modification of CytochromecRegulates CytochromecOxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling
일반논문 2020-04-01 Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis
일반논문 2020-04-01 Non-invasive treatment with near-infrared light: A novel mechanisms-based strategy that evokes sustained reduction in brain injury after stroke
일반논문 2019-12-01 Serine-47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase-3 activity
일반논문 2019-11-01 Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation
일반논문 2019-02-01 Tissue-specific regulation of cytochrome c by post-translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis
일반논문 2018-12-12 Myricetin Exerts Anti-Obesity Effects through Upregulation of SIRT3 in Adipose Tissue
일반논문 2018-05-01 AEROBIC EXERCISE PRECONCEPTION AND DURING PREGNANCY ENHANCES OXIDATIVE CAPACITY IN THE HINDLIMB MUSCLES OF MICE OFFSPRING
일반논문 2018-04-01 Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury (vol 8, 2018)
일반논문 2018-02-01 Mitochondrial Structure, Function, and Dynamics: The Common Thread across Organs, Disease, and Aging
일반논문 2017-08-01 HPV-associated differential regulation of tumor metabolism in oropharyngeal head and neck cancer
일반논문 2017-05-01 Tissue-and Condition-Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease
일반논문 2017-01-01 Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney IMPLICATIONS FOR AMP KINASE
일반논문 2016-09-01 ATP5B regulates mitochondrial fission and fusion in mammalian cells
일반논문 2016-08-01 COX7AR is a stress inducible mitochondrial COX subunit that promotes breast cancer malignancy
일반논문 2016-01-01 (-)- EPICATECHIN ATTENUATES DEGRADATION OF MOUSE OXIDATIVE MUSCLE FOLLOWING HINDLIMB SUSPENSION
일반논문 2015-09-01 Inhibition of N-Methyl-d-aspartate-induced Retinal Neuronal Death by Polyarginine Peptides Is Linked to the Attenuation of Stress-induced Hyperpolarization of the Inner Mitochondrial Membrane Potential.
일반논문 2015-08-01 Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines
일반논문 2015-06-01 Molecular Mechanisms and Therapeutic Effects of (-)- Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration
일반논문 2015-03-01 (-)-Epicatechin combined with 8 weeks of treadmill exercise is associated with increased angiogenic and mitochondrial signaling in mice
일반논문 2015-01-01 Betaine is a positive regulator of mitochondrial respiration.
일반논문 2015-01-01 MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism
일반논문 2014-11-01 Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency
일반논문 2014-09-01 Energy crisis: The role of oxidative phosphorylation in acute inflammation and sepsis
일반논문 2014-05-29 Mitochondrial DNA Variant in COX1 Subunit Significantly Alters Energy Metabolism of Geographically Divergent Wild Isolates in Caenorhabditis elegans
일반논문 2014-04-30 Regulation of cytochrome c in respiration, apoptosis, neurodegeneration and cancer: the good, the bad and the ugly
일반논문 2014-03-01 Insertion of Proteolipid Protein into Oligodendrocyte Mitochondria Regulates Extracellular pH and Adenosine Triphosphate
일반논문 2014-03-01 Increased mitochondrial activity in renal proximal tubule cells from young spontaneously hypertensive rats
일반논문 2014-02-07 Deletion of the Cardiolipin-specific Phospholipase Cld1 Rescues Growth and Life Span Defects in the Tafazzin Mutant IMPLICATIONS FOR BARTH SYNDROME
일반논문 2014-02-06 Epicatechin Stimulates Mitochondrial Activity and Selectively Sensitizes Cancer Cells to Radiation
일반논문 2013-11-01 Cytochrome c Is Tyrosine 97 Phosphorylated by Neuroprotective Insulin Treatment
학술발표 2013-06-17 (-)-Epicatechin improves mitochondrial function through activation of cytochrome c oxidase
학술발표 2013-06-17 Phosphorylation of Bovine kidney cytochrome c
일반논문 2013-06-01 (-)-Epicatechin is associated with increased angiogenic and mitochondrial signalling in the hindlimb of rats selectively bred for innate low running capacity
학술발표 2013-05-14 The role of cytochrome c oxidase subunit 4 isoform 2 in lung physiology
학술발표 2013-05-06 Do mitochondria cause essential hypertension? Increased renal proximal tubule bioenergetic activity prior to the onset of sustained hypertension in spontaneously hypertensive rats
학술발표 2013-05-06 CHCHD2, a new regulator of mitochondrial metabolism
일반논문 2013-03-01 Similar skeletal muscle angiogenic and mitochondrial signalling following 8 weeks of endurance exercise in mice: discontinuous versus continuous training
일반논문 2012-10-01 Deletion of heart-type cytochrome c oxidase subunit 7a1 impairs skeletal muscle angiogenesis and oxidative phosphorylation
일반논문 2012-09-01 Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology
일반논문 2012-05-01 Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: Respiration, apoptosis, and human disease
일반논문 2012-04-01 (-)-Epicatechin maintains endurance training adaptation in mice after 14 days of detraining
일반논문 2012-04-01 Multiple phosphorylations of cytochrome c oxidase and their functions
일반논문 2012-04-01 Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation
일반논문 2012-03-01 TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy
일반논문 2012-03-01 Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy
일반논문 2012-03-01 TLR4-Mediated AKT Activation Is MyD88/TRIF Dependent and Critical for Induction of Oxidative Phosphorylation and Mitochondrial Transcription Factor A in Murine Macrophages
일반논문 2011-05-01 The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis
일반논문 2010-08-01 Phosphomimetic Substitution of Cytochrome c Tyrosine 48 Decreases Respiration and Binding to Cardiolipin and Abolishes Ability to Trigger Downstream Caspase Activation
일반논문 2010-07-01 Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function
일반논문 2010-06-01 Theophylline treatment improves mitochondrial function after upper cervical spinal cord hemisection
일반논문 2010-02-01 A suggested role for mitochondria in Noonan syndrome
일반논문 2009-12-01 Epidermal Growth Factor Receptor Translocation to the Mitochondria REGULATION AND EFFECT
일반논문 2009-09-01 Mitochondrial Dysfunction in a Neural Cell Model of Spinal Muscular Atrophy
일반논문 2009-08-01 Different proteolipid protein mutants exhibit unique metabolic defects
일반논문 2009-03-01 ISOLATION OF REGULATORY-COMPETENT, PHOSPHORYLATED CYTOCHROME C OXIDASE
일반논문 2008-10-01 Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease
일반논문 2008-07-01 Tumor necrosis factor alpha inhibits oxidative phosphorylation through tyrosine phosphorylation at subunit I of cytochrome c oxidase

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